The optimum combination is to use two pieces from the Windloft Perfection set and four pieces from the Issatar Imbued set.
Issatar Imbued Set & Bonuses
Issatar At Rest
Issatar Undone
Issatar Enraged
Issatar’s Open Hand
Issatar Contained
Issatar The Brute
Set Items:
Name
Slot
Dungeon
Issatar At Rest
Neck
Mad King’s Breach
Issatar Undone
Ring 1
Cavern of Echoes
Issatar Enraged
Ring 2
Pit of Anguish
Issatar’s Open Hand
Hands
Forgotten Tower
Issatar Contained
Waist
Tomb of Fahir
Issatar The Brute
Feet
Destruction’s End
Set Bonus:
2/6 Bonus – You get a 2-second, 30% boost in movement speed after every enemy you destroy.
4/6 Bonus – For every 5% increase in movement speed, the damage delivered increased by 2.5%, up to a maximum damage increase of 25%.
6/6 Bonus – A 10% chance to obtain an orbiting soul orb that delivers 263 damage to enemies for 10 seconds is awarded to you each time you defeat an opponent. Not more than one soul orb per 40 seconds may be obtained.
Windloft Perfection Set & Bonuses
Wisdom’s Edge
Fairfleet
Foulfleet
Hurtling Steel
Whipcrack
Stump-Stir
Set Items:
Name
Slot
Dungeon
Wisdom’s Edge
Neck
Forgotten Tower
Fairfleet
Ring 1
Mad King’s Breach
Foulfleet
Ring 2
Pit of Anguish
Hurtling Steel
Hands
Tomb of Fahir
Whipcrack
Waist
Destruction’s End
Stump-Stir
Feet
Kikuras Rapids
Set Bonus:
2/6 Bonus – Acquire Thousand Winds, which will give you a 15% movement speed boost. If you take damage, Thousand Winds becomes inactive for three seconds.
4/6 Bonus – 20% more damage is dealt by you when Thousand Winds is in effect.
6/6 Bonus – Acquire a shield that, while Thousand Winds is active, protects you from damage five times. This shield can only be obtained once every 40 seconds.